Your safety, from intake to medication
GLP-1 is prescription medication, and that calls for real medical guidance. That's why we built Lean Clinic around Dutch healthcare rules: a doctor reviews every request, your medication comes from a registered pharmacy, and you're monitored throughout.
Not for everyone, and that is on purpose
Lean Clinic is intended for adults with a medical indication for obesity treatment: a BMI of 30 or higher, or a BMI of 27 or higher with a weight-related health condition. If you do not qualify, or if treatment is not safe for you, you are declined and pay nothing.
- BMI of 30 or higher (obesity)
- Or BMI of 27+ with a health condition
- Adults between 18 and 75 years
- Pregnancy or breastfeeding
- Under 18 years old
- Type 1 or type 2 diabetes
- Active eating disorder
Other medical conditions can also be a reason. We review your full history in the questionnaire and the consultation.
Is losing weight with GLP-1 safe?
For adults with a medical indication, GLP-1 is a safe treatment, provided a doctor assesses beforehand whether the medicine suits you and keeps following you while you use it. It is not without risk: gastrointestinal complaints are common, and in rare cases more serious problems occur, such as an inflamed pancreas or gallstones.
GLP-1 medication has been assessed and authorised by the European Medicines Agency and the Dutch Medicines Evaluation Board, and has been studied in large clinical trials. In diabetes care this group of medicines has been prescribed for years. For weight treatment the track record is shorter, so knowledge about the very long term is still growing.
What is common
Nausea, constipation, diarrhoea and a bloated feeling. Usually in the weeks after a dose increase, and usually the complaints ease once your body adjusts to the dose.
What is rare, but serious
An inflamed pancreas, gallstones or dehydration from persistent vomiting. Rare, which is exactly why it matters to recognise it. If you have severe abdominal pain that does not pass, contact a doctor straight away.
Who it is not suitable for
We prescribe nothing during pregnancy or breastfeeding, after a previous pancreatitis, with an active eating disorder, or with medullary thyroid cancer in the family. The doctor goes through your history and your current medication before any prescription is issued.
What lowers the risk
Building the dose up slowly makes the biggest difference, because complaints peak just after an increase. On top of that, enough protein and exercise keep your muscle mass up, and your care team reads your weekly check-in.
This page offers general information and does not replace medical advice. Whether GLP-1 is safe in your situation is for a doctor to judge after going through your health history.
How we safeguard your safety
Before you receive anything, you go through a medical check that follows the guidelines for prescribing GLP-1 medication.
Medical questionnaire
After creating your account, you fill in a comprehensive questionnaire about your health, medication and lifestyle.
Medication overview
The doctor needs your current medication details. You'll get clear instructions on how to share this with us safely, so the doctor has a complete picture.
Identity verification
Through a secure check, you confirm your identity with a valid ID. This is a legal requirement for prescribing medication.
Video consultation with the doctor
You always have a personal video call with a Dutch doctor. They assess your situation, discuss the treatment plan and explain the risks and side effects.
Medication monitoring
Consent for the LSP is required. This allows the pharmacy to carry out full medication monitoring, and your medication details are shared securely with other healthcare providers.
Medical questionnaire
After creating your account, you fill in a comprehensive questionnaire about your health, medication and lifestyle.
Medication overview
The doctor needs your current medication details. You'll get clear instructions on how to share this with us safely, so the doctor has a complete picture.
Identity verification
Through a secure check, you confirm your identity with a valid ID. This is a legal requirement for prescribing medication.
Video consultation with the doctor
You always have a personal video call with a Dutch doctor. They assess your situation, discuss the treatment plan and explain the risks and side effects.
Medication monitoring
Consent for the LSP is required. This allows the pharmacy to carry out full medication monitoring, and your medication details are shared securely with other healthcare providers.
Ongoing support
At Lean Clinic, you're never on your own. You get all the tools you need.
Weekly check-ins
We monitor your progress and side effects
Learning modules
New modules on lifestyle and behaviour every week
Live chat
Direct contact with your care team
Follow-up consultations
Regular follow-up consultations with a doctor
“Medication gets you started, behaviour change keeps you on track.”
Jake Prins
Co-founder
Genuine medication, safely delivered
Your medication does not come from a web shop or abroad, but from De ThuisApotheek: a registered Dutch pharmacy. So you can be sure you have the right, genuine product.
Registered Dutch pharmacy
Your prescription goes straight to De ThuisApotheek, which prepares your medication and delivers it discreetly.
No counterfeits or grey imports
Only original GLP-1 medication registered in the Netherlands. Never via unknown intermediaries.
Medication monitoring via the LSP
With your consent, the pharmacy checks for interactions with other medicines you take.
Safety per medicine
Every medicine has its own patient leaflet, its own side effects and its own group of people it is not suitable for. The information page for each medicine sets out what is known.
Ozempic
Semaglutide, authorised for type 2 diabetes and prescribed off-label for weight.
Read the information pageMounjaro
Tirzepatide, which acts on two gut hormones at once rather than one.
Read the information pageWegovy
Semaglutide at the dose authorised for the treatment of obesity.
Read the information pageOfficially registered and verifiable
Our registrations are public. Click through to check them yourself.
Frequently asked questions about safety
The questions clients ask most often before they start.
Ready to start safely?
Fill in the questionnaire and let a BIG-registered doctor assess whether medical weight loss is right for you. If you decide not to continue after your consultation, or you're not eligible, you always get your money back.
Blog about medical weight loss
Read our articles about medical weight loss, lifestyle, nutrition, medication, obesity, exercise and healthy living.
Wegovy pil goedgekeurd in Europa: de eerste GLP-1 pil voor gewichtsbeheersing
De Europese Commissie heeft de Wegovy pil goedgekeurd als eerste GLP-1 pil voor gewichtsbeheersing in de EU. Wat is er precies goedgekeurd en wanneer komt de pil naar Nederland?
Ontsteking en obesitas: waar start de vicieuze cirkel?
Een diepgaande blik op de complexe relatie tussen obesitas en chronische ontsteking, hoe ze elkaar versterken, en hoe leefstijl en nieuwe behandelingen zoals GLP-1 medicatie deze cirkel kunnen doorbreken.
GLP-1 ervaringen: wat kun je verwachten bij afvallen?
Wat zijn de ervaringen met GLP-1 bij afvallen? Lees wat je realistisch kunt verwachten: hoe het voelt, veelvoorkomende bijwerkingen, het verloop per fase en waarom ervaringen per persoon verschillen.